地區(qū): | 上海 |
簡(jiǎn)介: | 上海 |
提供商: | SABio |
服務(wù)名稱: | PCR芯片 |
核受體與輔助調(diào)節(jié)因子RT2 Profiler? PCR Array可以同時(shí)測(cè)定84個(gè)編碼核蛋白受體和輔助調(diào)節(jié)子的基因。芯片中包括甲狀腺和類固醇激素受體、視黃醇和維他命D受體以及孤兒受體。核受體活性的輔助激活因子和輔助抑制因子、染色體修飾酶也包含其中。通過(guò)實(shí)時(shí)定量PCR的方法,研究者即能夠利用該芯片簡(jiǎn)單可靠地同時(shí)檢測(cè)核受體和輔助調(diào)節(jié)因子相關(guān)基因的表達(dá)。 Nuclear Receptors: Androgen Receptors and Related Molecules: AR, MED14, MED17, MED12, MED4, NR1I3, MED1, MED13, MED24, MED16. Estrogen Receptors and Related Molecules: ESR1, ESR2, NCOA6, PPARGC1B. Glucocorticoid Receptors and Related Molecules: NCOA6, NR3C1. Retinoic Acid Receptors and Related Molecules: HMGA1, NCOA6, RARA, RARB, RARG, RXRA, RXRB, RXRG. Thyroid Hormone Receptors and Related Molecules: BRD8, MED14, MED17, MED12, MED4, NCOA3, NCOA4, NCOA6, NR1D1, NR1H3, NR1I3, NR2F6, MED1, THRA, MED13, MED24, MED16, THRB. Vitamin D Receptors and Related Molecules: MED14, MED17, MED12, MED4, MED1, MED13, MED24, MED16, VDR. Steroid Hormone Receptors: ESRRA, ESRRB, ESRRG, HNF4A, NR0B1, NR0B2, NR1D1, NR1D2, NR1H2, NR1H3, NR1H4, NR1I2, NR2C1, NR2C2, NR2E3, NR2F1, NR2F2, NR2F6, NR3C2, NR4A1, NR5A1, NR6A1, PPARA, PPARD, PPARG, RARA, RARB, RARG, RORA, RXRA, RXRB, RXRG, THRA, THRB, VDR. Other Nuclear Receptors: AHR, TRIP4. Transcription Factors and Regulators: Ligand-dependent Nuclear Receptor Transcription Coactivators: MED14, MED17, HMGA1, MED12, MED4, NCOA6, MED1, PPARGC1A, PPARGC1B, MED13, MED24, MED16. Positive Regulators of Transcription: ARNT, BRD8, CREBBP, ESR2, KAT5, NCOA1, NCOA2, NCOA3, NCOA4, NFKB2, NR1H3, NR1I2, NR1I3, NR2C2, NR2F1, NR5A1, NRIP1, PSMC3, RARA, RXRA, RXRB, TRIP4. Negative Regulators of Transcription: COPS2, HDAC4, HDAC5, HDAC6, HDAC7, NCOR1, NCOR2, NR0B2, NR1D1, NR2F2, PSMC3, PSMC5, THRA, THRB. Other Transcription Factors and Regulators: AHR, AR, ESR1, ESRRA, ESRRB, ESRRG, HDAC1, HDAC2, HDAC3, HNF4A, ITGB3BP, MTA1, NOTCH2, NR0B1, NR1D2, NR1H2, NR1H4, NR2C1, NR2E3, NR2F6, NR3C1, NR3C2, NR4A1, NR6A1, KAT2B, PPARA, PPARD, PPARG, RARB, RARG, RBPJ (RBPSUH), RORA, RXRG, VDR. Chromatin Modification Molecules: Histone Acetylation: KAT5, NCOA1, NCOA3, KAT2B. Histone Deacetylation: HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7. Other Chromatin Modification Molecules: ESR1, HMGA1, NCOA6, PPARGC1B. Other Nuclear Receptor Co-regulators: DDX5, TGS1, NONO. |