淋巴瘤PCR芯片 Lymphoma PCR Array
| 地區(qū)： | 上海 |
| 簡介： | 上海 |
| 提供商： | SABio |
| 服務(wù)名稱： | PCR芯片 |
淋巴瘤PCR芯片可用于研究與淋巴瘤發(fā)展，疾病分型，預(yù)后以及治療反應(yīng)中關(guān)鍵的84個基因的表達。該芯片包含有和淋巴瘤相關(guān)的信號通路包括細胞黏附，細胞周期，免疫以及炎癥反應(yīng)，PI3K/AKT，T細胞分化的關(guān)鍵基因；芯片上還包含有這些通路中淋巴瘤治療靶標(biāo)，淋巴瘤樣品中常規(guī)檢測的基因以及啟動子發(fā)生甲基化變化的基因。利用實時定量PCR，研究者可以方便并且可信地對與淋巴瘤發(fā)生發(fā)展以及轉(zhuǎn)移相關(guān)的基因進行同時檢測。 Differentially Methylated Promoters: AFF1, ATM, CADM1 (TSLC1), CCND1, CDH1 (E-Cadherin), CDH13, CDKN1C (p57KIP2), CDKN2B (p15INK4B), CDKN2C (p18INK4C), DAPK1, DLC1, FHIT, GSTP1, HIC1, HRK, ID4, LRP1B, MLH1, MYOD1, RASSF1, RBP1, SLC19A1, TIMP2, TIMP3. DLBCL Survival: ASB13, BCL6, ITPKB, LMO2, LRMP, MYBL1, PAG1, PTK2, TTC9, VGLL4. Follicular Lymphoma Survival: C1QA, CCR1, F8, FCGR1A, FLT3LG, STAT4, TLR5, TNFRSF1B, TNFSF13B. Lymphoma Therapeutic Targets: BCL6, BIRC5, BTK, CD22, CD40 (TNFRSF5), CD80, CXCR4, FCGR1A, HSP90AA1, MCL1, MS4A1, MTOR, NOTCH1, PARP1 (ADPRT1), PTK2, SRC, SYK, TGFB1, TNFSF13B. Inflammatory Response: C1QA, CCR1, CD40 (TNFRSF5), CD40LG (TNFSF5), CSF3 (GCSF), CXCR4, F8, IL6, NFKB1, TGFB1, TLR5, TNF, TNFRSF1B. Immune System Process: BCL6, C1QA, CADM1 (TSLC1), CD2, CD4, CD40 (TNFRSF5), CD5, CD79A, CD80, FCER2, IFNG, IL2, IL6, ITPKB, PDLIM7, PTPRC, SYK, TGFB1, TNFSF13B. T Cell Differentiation: BCL2, CD3D, CD4, CD8A, ITPKB, IL2, PTPRC, SYK, TGFB1, TP53. Cell Adhesion: BCL2, CADM1 (TSLC1), CCR1, CD2, CD22, CD34, CD4, CD40LG (TNFSF5), CD47, CD8A, CDH1 (E-Cadherin), CDH13, DLC1, F8, IL2, NCAM1, PTPRC, SRC, SYK, TNF. Cell Cycle: ATM, BCL2, BIRC5, CCND1, CDKN1C (p57KIP2), CDKN2B (p15INK4B), CDKN2C (p18INK4C), ID4, IFNG, MKI67, MLH1, MYC, RASSF1, TGFB1, TP53. PI3K/AKT Signaling: ALK, BCL2, BTK, CCND1, CCR1, CD2, CD4, CD40 (TNFRSF5), CD40LG (TNFSF5), CSF3 (GCSF), CXCR4, HSP90AA1, IL2, IL6, MTOR, PTK2, SYK, TGFB1, TIMP2, TIMP3, TNFRSF1B, TNFSF13B, TP53. Gene Fusion: ALK, MME. DNA Repair: DNTT |
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